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Valium or commonly known by its generic name Diazepam, is classified as a benzodiazepine derivate drug. It is regularly used to treat a wide range of conditions such as anxiety, seizures, muscle spasm, insomnia, and Meniere’s Disease. It possesses several characteristics of benzodiazepine drugs like anticonvulsant, sedative, hypnotic, anxiolytic, amnestic, and muscle relaxant properties.
The primary indication of Valium administration is to treat anxiety, symptoms of acute alcohol or opiate withdrawal and insomnia. Since tolerance to the anticonvulsant effects of Valium may occur within 6 to 12 months of administration, it is not commonly used for long – term medication for epilepsy. Also, Valium is quite useful addition for treating muscle spasm resulting from reflex spasm to local pathology, stiff man syndrome, athetosis and spasticity due to upper neuron disorders.
Oral preparations of Valium are available in 2 mg, 5 mg, and 10 mg tablets. For the treatment and management of anxiety disorders and anxiety symptoms relief it is recommended to use 2 mg to 10 mg, two to four times daily, depending of the severity of the symptoms. For additional therapy of skeletal muscle spasm, it is advisable to use 2 mg to 10 mg, three to four times each day. Also, for symptomatic relief in acute alcohol withdrawal, it is recommended to administer 10 mg, three to four times during the initial 24 hours and reducing the dosage to 5 mg, three to four times each day as necessary.
Valium has various adverse effects which are usually seen in most benzodiazepines. The most common side effects include depression, somnolence, and impaired motor function, suppression of REM sleep, cognitive deficits, and anterograde amnesia. Rare paradoxical adverse effects may include irritability, nervousness, muscle cramps, insomnia, violence and rage.
Just like other benzodiazepines, Valium has a wide range of contraindications. The use of Valium must be avoided in patients with conditions such as severe liver or kidney deficiencies, severe sleep apneau, severe respiratory disorders, psychosis, pregnancy or breast feeding, Myasthenia gravis, and hypersensitivity or allergies of benzodiazepines.